I am honored to publish this special issue of “Scar” in The Journal of Wound Technology. This issue mainly consists of papers presented at the conference, “International Scar Meeting in Tokyo 2010”, which was held on November 30th and December 1st.

The purpose of this meeting was to facilitate the discussion of treatment of scars and fibrotic disorders and the analysis of these mechanisms from international viewpoints. This meeting was co-organized with the 5th annual meeting of the Japan Scar Workshop which was established in 2006, and the Japanese Society for Wound Healing, established in 1971 provided scientific support for the International Scar Meeting in Tokyo 2010.

Throughout the meeting, many topics related to scars such as various treatments of post-burn scars, traumatic scars, keloids and hypertrophic scars, aesthetic management of scars, reconstructive surgery of scar contractures, and basic research on fibrotic disorders, were discussed in depth. Participants came from 23 countries and a total of 105 papers were presented and discussed including 21 invited lectures, 6 papers for panel discussion, 52 papers for general oral presentations and 26 papers for general poster presentations.

The signifiance of this special issue comes from the variety of viewpoints on scars and fibrotic disorders – topics discussed partially in the area of plastic surgery – by experts in the fields of plastic surgery, dermatology, aesthetic surgery and wound healing. I hope this special issue contributes to the development of scar management and advancement of basic research worldwide.

Rei Ogawa,
Secretary General,
International Scar Meeting in Tokyo 2010

Contents

Special issue: Scar. International Scar Meeting 2010. November 30th and December 1st 2010

Surgery and chemotherapy of keloids: use of low dose 5-FU for treatment and relapse prevention
Xiaoli Wu, Zhen Gao, Wei Liu

Intralesional cryosurgery for enhancing the involution of hypertrophic scars and keloids, a new effective technology based on experimental and clinical data
Yaron Har-Shai

Functional analysis of IL-6 signaling pathway in kloid pathogenesis and its therapeutic implication
Mamiko Tosa, Mohammad Ghazizadeh, Masahiro Murakami, Hiko Hyakusoku

Treatment of traumatic scars using plasma skin regeneration (PSR) system and fractional lasers
Taro Kono, William Frederick Groff, Hiroyuki Sakurai, Takashi Yamaki

Pathogenesis of diabetic complications through bone marrow-derived cells
Akinori Hara, Norihiko Sakai, Takashi Wada

Fibrosis and fibrotic disorder of ogans throughout the body modulation of vocal fold scar fibroblasts by adipose derived stem cells in vitro
Yoshihiko Kumai

Pathomechanism of ligamentum flavum hypertrophy is similar to that of hypertrophic scar formation during wound healing
Koichi Sairyo, Rei Ogawa, Akira Dezawa

The combined use of recombinant human epidermal growth factor (rh-EGF, Nepidermin) and fractional carbon dioxide laser in reducing cutaneous scar formation
Muneera Ben-Nakhi, Eun Jung Park, Joon Pio Hong

Human recombinant basic fibroblast growth factor (bFGF) improves scar quality such as softness, elasticity, of the scar and stratum corneum function and color-match as accelerates wound healing
Sadanori Akita, Kozo Akino, Akiyoshi Hirano

Of Mice and Men: Mechanical signaling and scar formation across species
Ravi K. Garg, Victor W. Wong, Geoffrey C. Gurtner

Medical needling
Hans-Oliver Rennekampff, Matthias Aust, Peter M. Vogt

Current keloid and hypertrophic scar treatment algorithms and our recent trials
Rei Ogawa, Satoshi Akaishi, Teruyuki Dohi, Takeshi Iimura, Hiko Hyakusoku

Forces and matrices in wound healing
Dennis P. Orgill, Rei Ogawa

Treatment of hypertrophic scars using pulsed dye lasers
Taro Kono, William Frederick Groff, Hiroyuki Sakurai, Takashi Yamaki

Experience of the pressure method using sponge for hypertrophic scar treatment of the hand
Hajime Takahashi, Koji Kurihara

Non-contact mode long pulse Nd:YAG laser therapy for keloids and hypertrophic scars
Satoshi Akaishi, Sachiko Koike, Teruyuki Dohi, Kyoko Kobe, Hiko Hyakusoku, Rei Ogawa

Strategy for treating ear keloids
Chenyu huang, Satoshi Akaishi, Teruyuki Dohi, Hiko Hyakusoku, Rei Ogawa

Identification and characterization of cartilage oligomeric matrix protein (COMP) as a novel pathogenic factor in keloids
Shigeki Inui, Fumie Shono, Takeshi Nakajima, Ko Hosokawa, Satoshi Itami

In vitro and in vivo studies on antifibrotic effects of dextran sulphate
Chao-Kai Hsu, Sheau-Chiou Chao, J. Yu-Yun Lee, Mei-Hui Yang, Jian-You Chen, Feng-Jie Lai

In vitro and in vivo evidence of pathogenic roles of Hic-5/ARA55 in keloids through Smad pathway and profibrotic transcription
Shigeki Inui

Preliminary measurement of atmospheric condition during wound repair
Hitomi Sano, Shigeru Ichioka

Autologous fat graft and scar treatment
Fabio Caviggioli, Francesco Klinger, Davide Forcellini, Guido Cornegliani, Marco Klinger

Combination laser treatments and classification of cutaneous scars
Yongsoo Lee

Ablative fractional erbium-yag laser for the treatment of atrophic post-acne scarring
Gerd G. Gauglitz, Daniel S. Müller, Peter Kaudewitz, Jürgen Schauber, Thomas Ruzicka

Autologous fat graft: an innovative solution for post-mastectomy pain syndrome tratment
Fabioo Caviggioli, Davide Forcellini, Valeriano Vinci, Andrea Lisa, Marco Klinger

Cosmetic and psychological effectiveness of rehabilitation Make-up for Post-burn Scar Patients
Takeshi Iimura, Reiko Kazki, Hiko Hyakusoku, Rei Ogawa

Integra as a biomechanical adjunct in reducing post-operative tendon adhesion formation – a retrospective clinical review
Mayer Tenenhaus, Dhaval Bhavsar, Bruce Potenza, Hans Oliver Rennekampff

Human homologous tissues as novel scaffolds for soft tissue reconstruction
L. Lancerotto, V. Vindigni, A. Volpin, G. Lago, A. Porzionato, T. Martinello, F. Bassetto

In vivo guided healing of microvascular structures
V. Vindigni, F. Bassetto, L. Pandis, B. Zavan, S. Lepidi, G. Abatangelo

Clinical data acquisitin of wounds and scars using a handheld three-dimensional stereophotographic system: first experiences
David B. Lumenta, Lars-Peter Kamolz, Harald Selig, Maike Keck, Manfred Frey

Scar rating scales: Examining the evidence
DR Megan Simons, DR Zephanie Tyack, DR Anneliese Spinks, Jason Wasiak

Influence of negative atmospheric pressure on cultured human dermal fibroblasts
Yoshihiro Takami, Jingping Guo, Shimpei Ono, Hakan Orbay, Rei Ogawa, Hiko Hyakusoku

Treatment of chronic ulcers by autologous blood injections
Mohammed Al Azrak, Rei Ogawa

Wound closure using human hair
Mohammed Al Azrak, Rei Ogawa

Management of radiation ulcers by surgical treatment
Vu Quang Vinh

Effectiveness of super-thin flaps in burn reconstructive surgery
Rei Ogawa, Shimpei Ono, Hiko Hyakusoku

Expansion-prefabricated crossing area supply super-thin flap: an experimental study and clinical application
Chunmei Wang, Junyi Zhang, Rong Jin, Jun Yang, Yunliang Qian

Management of contractures: A five-year prospective study at Komfo Anokye Teaching Hospital in Kumasi, Ghana
DR Emmanuel JK Adu

Children living with burn scarring: Can cosmetic camouflage improve psychosocial well-being?
Jessica James-Chadwick, Peter Newcombe, Graham Martin, Roy Kimble

About scar deformities of the foot
Babur M. Shakirov

Technique of tissue expansion for resurfacing as a treatment of postburn facial scars
Sifen Yang, Chunmei Wang, Junyi Zhang

Promoting wound healing activity using indian costus (Saussurea lappa)
Wadiah S. Backer, Solafa A. Zahran

A long term evaluation of Integra and split thickness skin grafts in acute burns and reconstructive surgery
Dai Qa Nguyen, Tom S. Potokar, Patricia Price

Evaluation of the donor site in patients who underwent reconstruction with a free radial forearm flap
Osamu Ito, Masumi Suzuki, Hiroki Miyashita, Takayuki Shirai, Minako Ito

Impact of maggot debridment therapy in patients with ischemic foot ulcer
Yoshiko Matsuda

Assessment of recurrence regions of keloid operated with Z-plasty
Kaho Matsuda, Fumiaki Shimizu, Miwako Oatari, Miyuki Uehara, Seiichi Sato, Daisuke Masuda, Hiroko Taneda, Aiko Kato

Measurement of keloid color
Masayo Aoki, Jyunichi Nakao, Teuyuki Dohi, Satoshi Akaishi, Tsuguhiro Miyashita, Hiko Hyakusoku, Rei Ogawa

Flap surgery for severe keloids: trials of flap surgery performed to reducetension
Teruyuki Dohi, Satoshi Akaishi, Shimpei Ono, Shimpei Nara, Takeshi Iimura, Hiko Hyakusoku, Rei Ogawa

Visual analysis of the regions of the body where keloids tend to occur
Yasutaka Omori, Satoshi Akaishi, Masataka Akimoto, Hiko Hyakusoku, Rei Ogawa

Histological and ultrastructural studies on the impact of antioxidants against the toxicity of certain heavy metals in the ovarian chicken
Fawzi I. Amer, El-Sayed Fikri A. El-Dawi, Osama A. H. Abo Zenada, Etedal A. H. Huwait

Diagnosis; assessment and classification of scar contractures
Rei Ogawa, Julian J. Pribaz

Small-wave incision method for hypertrophic scar reconstruction
Chenyu Huang, Shimpei Ono, Hiko Hyakusoku, Rei Ogawa

Effect of work and hand dexterity on the requirement for post-operative scar therapy, a retrospective study
N. Darhouse, A. Alexander